ema prac naion semaglutide very rare side effect june 2025 medicines such as Ozempic, Wegovy, and Rybelsus have been reviewed by UK and EU regulators in relation to a optic nerve condition called NAION. Swipe through for the key red PRAC assesses that NAION could

Its calming properties make it a compelling target for sleep-promoting therapies

It can also clog injection needles or pipettes

Common side effects include nausea, vomiting, diarrhea, constipation, and reduced appetitetypically transient but occasionally severe enough to require dose reduction or discontinuation

The procedure typically results in 5070% excess weight loss over 1824 months, but weight regain occurs in 2030% of patients within 510 years

Results improve further when combined with lifestyle modifications

This real-world data can support a range of use cases: Post-market surveillance: Monitor side effects, switching behavior, and persistence over time across diverse patient populations