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Ascorbate oxidase-dependent changes in the redox state of the apoplast modulate gene transcript accumulation leading to modified hormone signaling and orchestration of defense processes in tobacco

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Thus, the GSH/GSSG ratio reflects the oxidative state and can interact with redox couples to maintain appropriate redox balance in the cell

However, the evidence for meaningful clinical benefit in elderly populations remains preliminary, and the risk-benefit calculation must account for potential effects on glucose metabolism and cancer risk

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