Both classes of enzymes are vulnerable to inactivation by electrophiles such as dehydro-alanine (acrylate) glutathione when they are in their reduced form
The FDA recommends monitoring for progression of retinopathy, particularly during the initial months of treatment when blood glucose changes may be most dramatic
Patients and prescribers should weigh the tradeoffs: compounded products lack the rigorous stability, sterility, and potency testing that FDA-approved products undergo
If headaches persist beyond 6 weeks or worsen with each dose increase, medical evaluation is important to rule out other contributors
Gastric emptying slows because that is exactly what amylin is supposed to do
Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): a randomised, open-label, phase 3, non-inferiority trial