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When dehydration is detected by the central nervous system, antidiuretic hormone causes the kidneys to retain water (Al-Awqati 2012)

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However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)

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2D and E)

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In: Johnson FN (ed) Lithium Research and Therapy Academic Press: New York 1975

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