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Limited power to detect mortality benefits, given the relatively short follow-up durations in available studies

It impacts brain health

Immune Function Support : L-citrulline supports immune cell function through its role in the urea cycle and nitrogen metabolism, helping maintain optimal cellular energy production and supporting the body's natural defense mechanisms during periods of physical stress

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Since the sulfur in Cys-SH originates from Met, Cys production depends on the content of Met and on the metabolic activities of the trans-sulfuration pathway

With GLP-1based therapies, lower calorie intake, poor protein intake, inactivity, and rapid weight reduction can all contribute to lean-mass loss