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doi:10.2337/dc18-0078

After 2 weeks, repeated subcutaneous injections of these peptides significantly decreased body weight and fat mass

Am Fam Physician 96

doi: 10.1002/mc.23187 58 Ortiz-SnchezCEncarnacin-MedinaJParkJYMorenoNRuiz-DeyaGMattaJ

Trials show body weight reductions exceeding 22% at the highest dose (12mg/week), with its efficacy shown to be superior to Semaglutide across multiple study designs

These ligands are distributed downstream due to convective flow, resulting in an autologous chemotaxis mechanism, which can direct tumor cells towards the draining lymphatics, facilitating their metastatic spread [233]