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Shen, M

Cellpose: a generalist algorithm for cellular segmentation

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The authors reported, This confirms a profoundly altered myeloid profile in LC. The two findings were of a pair: monocytes tended to be immature and lacked the ability to surveil pathogens, while the T-cells appeared to be aged, highly activated, and headed for senescence and exhaustion

Conclusion Intraventricular administration of streptozotocin (3 mg/kg, single bilateral injection) induces not only neuronal damage but also reactive astroglial changes, pronounced tanycyte degeneration, disruption of the ependymal lining in the third and lateral ventricles, astrocytic dysfunction, and altered distribution of aquaporin-4 and connexin-43 in hypothalamic structures