Reminder: All proceeds from Ground Truths goes to support Scripps Research.
Matsunaga T, Hashimoto S, Yamamoto N, Kawasato R, Shirasawa T, Goto A, et al
Increased gas
GLP-1 receptor agonists (semaglutide, dulaglutide, liraglutide) can cause fatigue through reduced caloric intake, gastrointestinal side effects, and metabolic adjustment
While injectable tirzepatide and semaglutide dominate the weight loss market, researchers are actively working on oral formulations that could provide needle-free alternatives
The mechanism that lowers postprandial glucose also means the stomach retains contents longer, which is relevant to anyone with pre-existing gastroparesis or significant GI motility disorders, and is a theoretical consideration around procedures requiring an empty stomach