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Hair, skin, and nails: B12 supports cell reproduction, so hair, skin, and nail health can suffer when levels are low

While oral supplements are a common choice, they arent always effective if your body has trouble with absorption, making it difficult to get the full benefit

Such developments would provide researchers with an expanded toolkit for investigating the complex relationships between metabolism, aging, and disease, potentially accelerating discoveries across multiple fields of biomedical research

It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+

Nature Reviews Endocrinology .