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From a pharmacokinetic perspective, topical GHK-Cu has a distinct advantage: it acts locally rather than systemically

This was performed by high-pressure liquid chromatography using a LC-20A Shimadzu equipment (Shimadzu GmbH, Duisburg) with an interphase module (CBM-20A, Shimadzu GmbH) and electrochemical detection (ESA Biosciences, Inc., Chelmsford, MA), with the upstream electrode set at +100 mV (for compounds with low oxidation potential) and downstream electrode set between +100 and +650 mV (in +50 mV increments) for each injected standard to determine the optimum potential for detection

Targeting Apollo-NADP(+) to Image NADPH Generation in Pancreatic Beta-Cell Organelles