Gentle Patches GLP-1 contains herbal ingredients marketed as placebo alternatives to real semaglutide
References Transportation Security Administration
While the long-term safety and effectiveness of GLP-1RA for other indications like kidney disease and fatty liver still need verification, attention and research investment in GLP-1RAs for obesity and related conditions are keeping increasing, driving further scientific and medical advancements in metabolic diseases
30 Furthermore, a comparative trial of exenatide and liraglutide in T2DM subjects concluded that both incretin mimetics were associated with a significant reduction in body weight when compared to baseline (2.87 kg and 3.24 kg, respectively)
Semaglutide is the only GLP analog with a warning about diabetic retinopathy , which occured in 4.0% of patients (versus 2.7% with placebo)
DPP-4 (not described in detail in this article) is the enzyme responsible for degrading native GLP-1 and GIP in the body