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( A D ) Urine volume, urine sodium, urine chloride, and urine protein in normotensive control Glp1r VSM+/+ and Glp1r VSM/ male mice treated acutely with semaglutide (10 g/kg) 60 minutes prior to water gavage

The mean absolute bioavailability following intramuscular injection was approximately 14-19% in rats and 45-51% in beagle dogs, suggesting species-specific absorption characteristics relevant for dose translation to human applications

Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons