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By testing a theoretical range of human GLP-1R potencies at a once-weekly 50 mg dose and assuming the peptide retains its activity over the dosing period, simulations showed that a potency 40-fold less than the reference GLP-1-Fc(4) molecule should deliver equivalent GLP-1 activity to a 1.5 mg weekly dose of GLP-1-Fc(4) (Supplementary Fig

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EmousMvan den BroekMWijmaRBde HeideLJMvan DijkGLaskewitzAet alPrevalence of hypoglycaemia in a random population after Roux-en-Y gastric bypass after a meal test

10.1016/j.bbamcr.2020.118803 61 UkidveA.ZhaoZ.FehnelA.KrishnanV.PanD