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In situ photoimmunotherapy: a tumour-directed treatment for melanoma

in the liver, TMA is metabolized by the enzyme flavin-containing monooxygenase 3 (FMO3) to produce TMAO, which then enters the bloodstream

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Lipids are important in changing the structure and composition of cellular membranes and are also employed as energy sources during toxic biotransformation (Kayis et al

Glutathione is found in all tissues, with the highest concentrations in the liver, eyes, spleen, pancreas, and kidneys

SOD enzymes, including Cu-Zn SOD and Mn-SOD, facilitate spontaneous dismutation of superoxide radicals to generate H 2 O 2 , which is further removed by CAT and glutathione peroxidase enzymes (Saso and Firuzi, 2014)