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Preclinical studies showed preferential reduction of abdominal and visceral adipose tissue, suggesting favorable body composition changes even when total weight loss is moderate

The best time is as early as possible ideally within the first few weeks of beginning your medication

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Tirzepatide is a 39-amino-acid peptide engineered to bind and activate both the GIPR and the GLP-1R with comparable potency

Semaglutide 0.4 mg once-daily significantly improved NASH compared with placebo (NASH improved in 59% vs 17% of participants)

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