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Upon activation, GPER stimulates intracellular signaling cascades, including the PI3K/AKT and MAPK/ERK cascades, which further augment mitochondrial respiratory chain activity and ATP production [218]

Anti-TNF therapy: past, present and future

The doxorubicin accumulation seems to be at the basis of the positive effects of the innovative anti-neoplastic treatment known as cold physical plasma used on different melanoma cell lines