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It was first used to describe a cell death process induced by a small molecule called erastin, which inhibits the intake of cystine, resulting in glutathione depletion and inactivation of the phospholipid potentially toxic lipid peroxidase 4 (GPX4) (Yang et al., 2014)

Experimentally induced hypo-and hyper-thyroidism influence on the antioxidant defence system in adult rat testis

J Neurol Neurosurg Psychiatry 65(5):709716

This complex plays a sprawling role in the body, acting as a crucial regulator for processes like collagen synthesis, angiogenesis (the formation of new blood vessels), nerve outgrowth, and anti-inflammatory responses

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