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References 1 FASEB JournalBiological activities of thymosin beta-4 mapped to active peptide sequences, including the fragment marketed as TB-500

However, chronic stress, whether it is from toxins, poor diet, sleep deprivation, smoking, excess sugar, or other stressors, eventually exhausts glutathione levels

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doi: 10.1080/24750573.2018.1459005

For traumatic brain injury, the CAPTAIN program, summarized in a 2021 meta-analysis of two randomized trials and 185 patients, likewise reported modest benefit (Vester et al., 2021, pooled RCTs)