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In the liver without blood, only negligible amounts of food-derived Cys-Gly, -Glu-Cys, and glutathione disulfide were detected

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Clinical translation of ferroptosis modulators also faces significant bottlenecks, including bioavailability, limited tissue specificity, and potential toxicity or off-target [134, 135]

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It does not cause the irritation, photosensitivity, or barrier disruption associated with retinoids