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NICE NG28 recommends considering an SGLT2 inhibitor as the preferred option in adults with type 2 diabetes and chronic kidney disease or heart failure, unless contraindicated or not tolerated

Whether this is caused by a primary dopaminergic mechanism of action or indirectly by changes in other neurotransmitter systems, for example, glutamate or GABA, has not been ruled out [27]

Childhood trauma, four prior marriages, one well-worn coping pattern

Okoro EU, Zhao Y, Guo Z, Zhou L, Lin X, Yang H

People following these diets find it challenging to adhere to them long-term, as they may crave high-calorie but low-nutrient foods

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