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Nat Cell Biol (2014) 16(1):11826

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Asprey, the founder of Bulletproof Coffee -- a healthy buttery coffee mixture -- and the author of New York Times bestseller The Bulletproof Diet, talks to Spartan UP

As shown in Figure 4 , different amino acid pathways do not act independently during macrophage polarization, but instead form a highly coupled regulatory network through multiple levels, including metabolic flux direction, signal transduction, and epigenetic regulation