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The FDA has the authority to waive clinical trial requirements when the totality of evidence from analytical and PK/PD studies is sufficiently robust

Histoplasma Histoplasma capsulatum is endemic to the Midwest United States and Central America, though it has a global distribution [64]

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A comprehensive assessment of the full texts of the remaining 102 articles was performed for further eligibility evaluation

Many of the self-pay options connect patients with doctors on telehealth who will determine if they qualify for the drugs and write a prescription