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Increased levels of reactive oxygen species (ROS) reported in HIV-infected individuals promoted nucleic acid and lipid oxidations, resulting in elevated levels of 8-Oxoguanine (8-oxoG) and malondialdehyde (MDA), respectively, as evidences [3,6]

In clinical studies, it has been shown to promote feelings of fullness and reduce caloric intake, which may support weight management when combined with healthy lifestyle changes

The immunogenic death feature of pyroptosis, which releases cytokines that reshape the tumor immune environment and reduce immunosuppressive cells, underlies its significance in AML therapy by helping overcome immune escape (12)

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