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Acknowledgements The authors acknowledge Tabriz University of Medical Sciences

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The first such to be approved for therapy was exenatide, which was approved by the US Food and Drug Administration (FDA) in 2005 ( Inhibiting the Proteolytic Activity of DPP-4 and Early Animal Studies Inactivation of GLP-1 and GIP DPP-4 is a catalytic glycoprotein which releases a dipeptide from oligopeptides by cleaving the peptides between the second and the third amino acids from the N-terminal end provided that the second amino acid is alanine or proline (27, 28)

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330 (Pt 2), 695699 (1998)

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J Immunother Cancer 4:111 Kind F, Michalski K, Yousefzadeh-Nowshahr E, Meyer PT, Mix M, Ruf J (2022) Bone marrow impairment during early [177Lu] PSMA-617 radioligand therapy: haematotoxicity or tumour progression

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These symptoms often subside as the body adjusts, but they can deter some individuals from continuing the treatment

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[DOI] [PMC free article] [PubMed] [Google Scholar] Doyle ME, Theodorakis MJ, Holloway HW, Bernier M, Greig NH, Egan JM

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