Acknowledgements The authors acknowledge Tabriz University of Medical Sciences
The first such to be approved for therapy was exenatide, which was approved by the US Food and Drug Administration (FDA) in 2005 ( Inhibiting the Proteolytic Activity of DPP-4 and Early Animal Studies Inactivation of GLP-1 and GIP DPP-4 is a catalytic glycoprotein which releases a dipeptide from oligopeptides by cleaving the peptides between the second and the third amino acids from the N-terminal end provided that the second amino acid is alanine or proline (27, 28)
330 (Pt 2), 695699 (1998)
J Immunother Cancer 4:111 Kind F, Michalski K, Yousefzadeh-Nowshahr E, Meyer PT, Mix M, Ruf J (2022) Bone marrow impairment during early [177Lu] PSMA-617 radioligand therapy: haematotoxicity or tumour progression
These symptoms often subside as the body adjusts, but they can deter some individuals from continuing the treatment
[DOI] [PMC free article] [PubMed] [Google Scholar] Doyle ME, Theodorakis MJ, Holloway HW, Bernier M, Greig NH, Egan JM