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The choice matters

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UCWM (reference category) as the independent variable adjusted for headache frequency at baseline and in a second step also for weight loss to evaluate potential independent treatment effects of GLP-1-RAs

The FDA Adverse Event Reporting System (FAERS) contains reports of various gastrointestinal complications, though these reports have significant limitationsincluding underreporting, lack of denominator data, and inability to establish causality

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When guiding patients, it can be helpful to frame the conversation around three questions: What fits best into your daily routine