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doi: 10.1172/JCI38096 9 ArenasE

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In ACHIEVE-1 , the first of seven Phase 3 studies in people with type 2 diabetes, orforglipron reduced A1C by an average of 1.3% to 1.6% across doses compared to placebo at 40 weeks, starting from a baseline of 8.0%

Important tips: Allow vials to reach room temperature in a desiccator before opening to prevent moisture absorption Avoid repeated freeze-thaw cycles - only remove from freezer when ready to use Store in airtight containers with desiccant packs to prevent moisture exposure Keep away from direct light - use amber vials or wrap in aluminum foil Properly stored lyophilized peptides can remain stable for 2-4 years Once reconstituted with bacteriostatic water, peptides should be stored at 2-8C (refrigerator) and used within 2-4 weeks for optimal potency