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More recently, beta-amyloid was found to impair, but APOE4 itself to slightly improve, short-term memory among some 400 British participants without dementia (Lu et al., 2021)

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Because the immunohistochemical profile of atypical PN is not significantly different from melanoma, the study authors recommended treating atypical PN conservatively as borderline melanocytic lesions requiring complete excision with adequate margins and regular clinical follow-up

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Visits were scheduled at baseline (T0), after three (T3) and six months of therapy (T6), and a complete history and physical examination were performed each time