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Beyond these indications, there is evidence suggesting that L-Carnitine may be beneficial in the management of chronic heart failure and angina by improving exercise tolerance and reducing the risk of myocardial ischemia

Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility XIGDUO XR No animal studies have been conducted with XIGDUO XR to evaluate carcinogenesis, mutagenesis, or impairment of fertility

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The initial dose of amlodipine was 5 mg for 2 weeks with forced titration to 10 mg for 2 weeks, followed by the optional addition of hydrochlorothiazide 12.5 mg for 4 weeks

Int.J Cosmet.Sci 2011;33(6):519-526

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