semaglutide with metformin and Rybelsus: Managing the Interaction Semaglutide Impact on Metformin and

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NICE does not recommend it on the NHS due to insufficient evidence and the absence of a UK marketing authorisation

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If you get new health problems, like kidney problems, allergic reactions, upset stomach, or abdominal pain in your belly, talk to your healthcare provider about the most common side effects

The primary outcomes were weight and KCCQ-CSS changes

The STEP 8 trial directly compared these two drugs and found that semaglutide achieved 15.8% weight loss compared with 6.4% for liraglutide over 68 weeks