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253 The LDL receptor (LDLR) of hepatocytes is highly expressed and binds LDLs, clearing them from circulation

It is important to note that B12 levels should ideally be measured before commencing replacement therapy, as supplementation rapidly normalises biochemical markers, potentially obscuring the diagnosis

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396,397,398,399 GLP-1RAs and nerve cells GLP-1 can modulate peripheral nerves through the ERK (extracellular signal-regulated kinase) signaling pathway, reducing the occurrence of neurological dysfunction