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In older adults receiving semaglutide, not only did body composition improve, but physical performance metrics such as gait speed and mobility scores also showed measurable improvement

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There were no differences observed in the level of response on biopsy or MRI-PDFF to resmetirom or placebo treatment in patients with genetic risk alleles for PNPLA3 and TM6SF2 (Table) or TMC4 (not shown)

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These pleiotropic benefits may be particularly valuable for patients with obesity, metabolic syndrome, or type 2 diabetes who have residual cardiovascular risk despite adequate statin therapy