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PT-141 is a synthetic peptide that stimulates receptors in the brain to increase sexual arousal, rather than relying on blood flow like traditional ED medications
-Glutamylcysteinylserine a new homologue of glutathione in plants of the family Poaceae
May 2013;144(5):903-911.e3
In healthy male participants ages 18 to 45, PT-141 induced increased penis rigidity, erection duration, and overall sexual function in a dose-dependent manner (3)
The increased risk of amputation seen in the large, long-term Canagliflozin Cardiovascular Assessment Study (CANVAS) trial for canagliflozin, and select observational studies, merits further research but overall, there is currently no consistent evidence of SGLT2i exposure and increased risk of amputation
Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors
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