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The unsupervised clustering of 4453 fibroblasts was used to analyze the senescent cells in keloid and normal skin fibroblast based on senescence-associated marker genes, CDKN2A, TP53, CDKN1A (also known as p21 ) , LMNB1, H2AFX, TP53BP1, SFRP4, CCND1 and GLB1 according as previously reference 20,21
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doi:10.1016/s0002-9149(02)03144-2 8
L.PostA.van DijkP
Moreover, the potential crosstalk between the DHODH/CoQ10 and FSP1 pathways remains debated, with some evidence suggesting competitive and others indicating cooperative interactions
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