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For patients I see in [the] clinic, retatrutide may potentially be a highly impactful future tool to treat their obesity and transform their health trajectory. Participants also saw significant improvements to certain cardiovascular risk factors, including: While this medication has the potential to be the most effective option, long-term studies are not yet available, Ali told Healthline

"One of the things that I realized the very first time I took a GLP-1 was that all these years I thought that thin people just had more willpower, they ate better foods, they were able to stick to it longer, they never had a potato chip, and then I realized the very first time I took the GLP-1 that, 'Oh, they're not even thinking about it