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So, reducing hyperinsulinemia by GLP-1 analogies will contribute to weight loss and improve insulin sensitivity, and glycemic control in type 2 diabetes

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As further summarized in Table 1, these mechanisms include decreasing oxidative stress, increasing endogenous antioxidant defense capacities, counteracting inflammation by inhibiting NF-kB and release of inflammatory cytokines, mitigating renal fibrosis, and decreasing cell death, such as apoptosis, ferroptosis, and necrosis

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