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Senolytic therapies targeting anti-apoptotic pathways can eliminate senescent cells and enhance chemoradiotherapy efficacy of cancer 10,32

Nitric oxide (NO), natriuretic peptide type C (NPyC), and eicosanoids are all paracrine chemicals usually secreted by the endothelium

MPGES1 have a key role in inflammatory diseases and is high upregulated in tissues during inflammation and overexpressed in tumors 23

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