Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside
In June 2025, mazdutide received its first approval, in China, for use (in combination with diet control and increased physical activity) in long-term body weight management in adults with a body-mass index (BMI) of 28 kg/m 2 or with a BMI 24 kg/m 2 together with one or more weight-related comorbidity
The consistency of the preclinical data across multiple studies and laboratories supports the mechanistic hypothesis
When appetite is suppressed, this requires deliberate effort
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Weight Management These medications have also been shown to result in significant weight loss, which may in turn help to reduce the risk of diabetes complications and other obesity-related conditions