It has been studied since the early 2000s for its wound healing and tissue regeneration effects
The FDA added it to injectable semaglutide in January 2025, and it climbs the dose axis like everything else. Burning or tingling skin tracks the dose, not the weight lost, and an active-comparator study put the risk about twice that of another weight-loss drug. The mechanism is unsettled: the tempting "it is the drugs signaling arm" story is ruled out, because the strongest GLP-1 signaler in the class carries no such signal
[18] Chen N, Yang M, Zhou M, Xiao J, Guo J, He L
Stress axis Both touch the stress/HPA response
when Richard was around, we had to stay clean and behave and sit quietly in a chair and say nothing
If you eat a balanced diet, youre probably getting enough B12