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The strongest support comes from clinical evidence focused on treating vitamin B12 deficiency, not from general wellness claims What science supports The NIH Fact Sheet for Health Professionals shows that intramuscular B12 injections are effective at raising blood B12 levels and correcting deficiency

Clinical manifestations of B12 deficiency are diverse and can affect multiple organ systems

Pickart & Margolina 2014 Chelates free copper, reduces oxidative damage, and upregulates superoxide dismutase the body's primary antioxidant enzyme

Response: We believe that the commenter misunderstood how the health equity adjustment is applied under the Shared Savings Program

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