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In pathological conditions, erythrocytes can adhere to endothelial cells, which promotes the formation of microaggregates with consequent blood flow reduction [50]

And very recently, the results of a preclinical study were published and they indicated that the dual agonist approach may be more potent that GLP-1R agonism alone in a model of PD

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TB-500 Substantial Dose : The recommended dosing for TB-500 would follow the standard loading protocol, requiring milligram-level injections (e.g., 22.5 mg per injection, twice weekly)

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