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Conventionally, the main goal of radiotherapy has been to kill cancer cells, notwithstanding the local immunosuppression through various pathways such as vascular disruption and hypoxia, which might result in diminished recruitment of certain immune effector cells, exhaustion of effector T cells, and stimulation of regulatory T cells (321, 332334)

Importantly, this follow-up occurred in the absence of active lifestyle intervention, which the authors themselves note may have contributed to weight regain

Mitchell KG, Diao L, Karpinets T, Negrao MV, Tran HT, Parra ER, Corsini EM, Reuben A, Federico L, Bernatchez C, Dejima H, Francisco-Cruz A, Wang J, Antonoff MB, Vaporciyan AA, Swisher SG , Cascone T, Wistuba II, Heymach JV, Gibbons DL, Zhang J, Haymaker CL, Sepesi B

Vitamins and minerals are also widely used

Coto V, D'Alessandro L, Grattarola G, and et al

Melody is here to help as you adjust to a life with less (or no) alcohol