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Think about body temperature

PHP and IOP are designed for adults who have achieved initial stability and need ongoing clinical structure to protect and build on it

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Adding further complexity, GLP-1RAs can stabilize the BBB (219, 220), raising the possibility that drugs with limited baseline uptake may improve their own CNS access over time, particularly in aging or NDD states where BBB dysfunction is common

any infusion should have immediate access to emergency care

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