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Stoker M, Perryman M

Roughly 20% of active patients may improve spontaneously, while 40% stabilize and another 40% progress further with the disease

10.1016/j.cub.2012.02.016 Curr

Curr Med Sci

Retatrutide (LY3437943) is Eli Lillys experimental triple-agonist drug that activates: GLP-1 (Glucagon-like peptide-1) reduces appetite and slows digestion GIP (Glucose-dependent insulinotropic peptide) enhances insulin sensitivity Glucagon receptor increases fat metabolism and energy expenditure In phase-2 trials, Retatrutide achieved up to 24% body-weight reduction rivaling or even surpassing bariatric surgery outcomes

M.ChhatreD.et al (2009)