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10.1073/pnas.1313753110 7 BrutigamL.SchtteL

While various risk factors for enhanced APAP toxicity have emerged in the numerous experimental models of steatosis, including induction of Cyp2E1, reduced phase II metabolism, mitochondrial dysfunction, etc., opposite effects have also been described, suggesting that steatosis may not affect toxicity [180]

Compared to PDCs with high expression of VRK2, PDCs with low expression of VRK2 displayed a higher basal level of ROS and a lower basal level of GSH

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It is commonly found in animal products like meat, fish, and dairy

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