It adds to the growing body of evidence suggesting that GLP-1 receptor agonists may have neuroprotective properties, which could benefit patients beyond glucose control. However, as a clinician, Im also aware of the need for further research, including longer-term studies and randomized controlled trials, to better understand the mechanisms and validate these findings before making changes to my treatment approach, she added
[DOI] [PubMed] [Google Scholar] 42.Owen L.A., Hartnett M.E
Across the full treatment period in the STEP 1 trial of FDA-approved semaglutide (Wegovy), this corresponds to an average of roughly 1 to 2 pounds per week, though individual results varied and weight loss was not linear
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no clinical trials validate the combination
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