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GLP-1RA activate the cAMP/PKA pathway leading to phosphorylation of sodium-hydrogen exchanger 3 (NHE3) in renal proximal tubular cells, increasing natriuresis and diuresis and lowering blood pressure

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Currently, there is too immature an understanding of PD pathophysiology to make vagotomy a potential treatment method, and clarification through research is needed regarding the vagotomy-PD relationship

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