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Given this subjectivity and the lack of reliable clinical criteria for the diagnosis of melanocytic lesions, excision or biopsy of these lesions is commonly encountered in surgical pathology practice

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Transthyretin amyloid cardiomyopathy ATTR-CM is a progressive and life-threatening disease characterized by the aggregation of misfolded transthyretin (TTR) into insoluble amyloid fibrils within the heart

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