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159 The mitochondrial calcium uniporter (MCU) regulates Ca 2+ in mitochondria, and Ca 2+ uptake by MCU buffers the increase of cytoplasmic Ca 2+ and regulates mitochondrial oxidative phosphorylation

Homozygous missense mutations in SLC39A8 , which encodes ZIP8, result in Mn deficiency in humans (Riley et al., 2017

Research on GLP-1 receptor agonists shows that maintaining a fixed injection day produces more stable appetite suppression and metabolic effects than irregular timing

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In addition, in rat endplate chondrocytes, the intervention of IGF-1 up-regulated the expression of MMP-13 through the ERK pathway, thereby inhibiting the decomposition of cartilage [30]

Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH