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Tirzepatide may be prescribed when clinically appropriate after review of medical history, current medications, treatment goals and possible contraindications

A multicenter, single-blind, placebo-controlled, randomized clinical study (NCT04073368) assessed the effect of AXA1125 and AXA1957 on nonalcoholic fatty liver disease (NAFLD)

Single-agent optimization typically outperforms combination protocols in real-world practice

However, Brello's team offers guidance on managing these symptoms, and patients often note that side effects ease within weeks as their body adapts

The maximum maintenance dose is 15 mg once weekly