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Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma
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that pooled 50 randomized trials, GLP-1 RA were associated with a modest but significant increase in thyroid cancer risk (MH-OR 1.55, 95% CI 1.052.27), particularly in longer-duration studies
Still, experts warn that the findings are observational, meaning they show a connection rather than direct proof of cause and effect
Although the expression of GLP-1R in liver tissue is controversial, GLP-1RAs have been shown to act as regulatory pathways affecting metabolic disorders